Review of cryptogenic fibrosing alveolitis, including current treatment guidelines
نویسندگان
چکیده
منابع مشابه
Review of cryptogenic fibrosing alveolitis, including current treatment guidelines.
Cryptogenic fibrosing alveolitis (CFA), known as idiopathic pulmonary fibrosis in the USA, is characterised by inflammation and fibrosis of the alveoli and interstitium of the lungs, favouring the subpleural and basal regions. By definition the diagnosis demands that all known causes of pulmonary fibrosis have been excluded. It is now clear that the CFA population is comprised of a heterogeneou...
متن کاملPrognosis of cryptogenic fibrosing alveolitis.
We have analysed retrospectively 100 consecutive patients with cryptogenic fibrosing alveolitis, who were treated with corticosteroids and followed for at least three years. At the time of diagnosis biopsy specimens were available in 64 cases. The clinical, radiographic, physiological, and histological features and the response to steroid treatment have been correlated with the prognosis. An ea...
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The pathogenesis of cryptogenic fibrosing alveolitis (CFA) involves injury, an immune/inflammatory response and fibrosis. The cause of the injury is unknown, but the identification of serum autoantibodies makes an autoimmune aetiology attractive. The core study on which this commentary is based used novel cloning and serum screening technologies in order to identify new public and private autoa...
متن کاملThe prognosis of cryptogenic fibrosing alveolitis.
cases, 49-6 months in those dying from CFA only, and 48-4 months in those dying from CFA in whom the course of the illness was not influenced by corticosteroids. There was a wide variation in the natural course of the disorder, varying from death within a year of the onset of symptoms in five patients to prolonged survival with slow or arrested progress in four patients not treated with cortico...
متن کاملCryptogenic fibrosing alveolitis and lung cancer.
Lung cancer was found in 20 (9.8%) of 205 patients with cryptogenic fibrosing alveolitis (CFA) or 12.9% of the 155 patients in this series followed to death. An excess relative risk of lung cancer of 14.1 was found in patients with CFA compared to the general population of comparable age and sex, allowing for the lengths of follow-up of the CFA patients. The relative risk for male smokers was (...
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 2000
ISSN: 0032-5473
DOI: 10.1136/pmj.76.900.618